{"id":555,"date":"2020-02-18T16:50:16","date_gmt":"2020-02-18T15:50:16","guid":{"rendered":"https:\/\/www.sunrockbiopharma.com\/home\/"},"modified":"2026-06-23T10:27:06","modified_gmt":"2026-06-23T08:27:06","slug":"home","status":"publish","type":"page","link":"https:\/\/www.sunrockbiopharma.com\/es\/","title":{"rendered":"Anticuerpos de Nueva Generaci\u00f3n para Enfermedades Inflamatorias y C\u00e1ncer"},"content":{"rendered":"<p>[vc_row][vc_column css_animation=\u00bbfadeInUp\u00bb el_class=\u00bbbox-shadow\u00bb][vc_row_inner][vc_column_inner width=\u00bb1\/2&#8243;][vc_empty_space height=\u00bb80px\u00bb][vc_single_image image=\u00bb20&#8243; img_size=\u00bb\u00bb alignment=\u00bbcenter\u00bb][\/vc_column_inner][vc_column_inner width=\u00bb1\/2&#8243;][vc_empty_space height=\u00bb80px\u00bb el_class=\u00bbhidden-xs hidden-sm\u00bb][vc_column_text]SunRock Biopharma est\u00e1 desarrollando una cartera de anticuerpos <em data-start=\"322\" data-end=\"338\">first-in-class<\/em>, ADCs y programas de anticuerpos biespec\u00edficos para enfermedades inflamatorias y oncolog\u00eda, con una plataforma terap\u00e9utica l\u00edder dirigida a CCR9.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][vc_column_text]<\/p>\n<p style=\"text-align: center;\"><a class=\"btn\" href=\"\/es\/sunrock\">La Compa\u00f1\u00eda<\/a><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row foundry_padding=\u00bbpt64 pb64&#8243; el_id=\u00bbinmuno-oncology-open\u00bb][vc_column css_animation=\u00bbfadeInLeft\u00bb width=\u00bb1\/2&#8243;][vc_column_text]<\/p>\n<h2>Terapias Basadas en Anticuerpos Desarrolladas Mediante Innovaci\u00f3n Abierta<\/h2>\n<p>SunRock Biopharma transforma avances cient\u00edficos procedentes de la investigaci\u00f3n acad\u00e9mica en terapias diferenciadas basadas en anticuerpos para enfermedades con importantes necesidades m\u00e9dicas no cubiertas. A trav\u00e9s de una red global de socios cient\u00edficos, cl\u00ednicos e industriales, impulsamos el desarrollo de anticuerpos <em data-start=\"908\" data-end=\"924\">first-in-class<\/em>, ADCs y programas biespec\u00edficos para enfermedades inflamatorias y oncolog\u00eda.<\/p>\n<p style=\"text-align: center;\"><a class=\"btn\" href=\"\/es\/sunrock\/#sr-open\">Estrategia SRB<\/a><\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column css_animation=\u00bbfadeInRight\u00bb width=\u00bb1\/2&#8243;][vc_single_image image=\u00bb252&#8243; img_size=\u00bb\u00bb][\/vc_column][\/vc_row][vc_row foundry_background_style=\u00bbbg-primary\u00bb el_id=\u00bbccr9&#8243;][vc_column css_animation=\u00bbfadeInLeft\u00bb width=\u00bb1\/2&#8243; el_class=\u00bbprogram-img\u00bb][vc_single_image image=\u00bb334&#8243; img_size=\u00bbfull\u00bb alignment=\u00bbcenter\u00bb][\/vc_column][vc_column css_animation=\u00bbfadeInRight\u00bb width=\u00bb1\/2&#8243;][vc_column_text]<\/p>\n<h2>Programa CCR9<\/h2>\n<h3 data-section-id=\"1hryie8\" data-start=\"1048\" data-end=\"1054\">EII<\/h3>\n<p data-start=\"1056\" data-end=\"1536\">CCR9 desempe\u00f1a un papel clave en la enfermedad inflamatoria intestinal al dirigir el tr\u00e1fico de linfocitos patog\u00e9nicos hacia el intestino. En la colitis ulcerosa, su ligando CCL25 se detecta en el colon y sus niveles se correlacionan con la actividad de la enfermedad. Estudios cl\u00ednicos han demostrado un aumento de los niveles de c\u00e9lulas T CCR9+ en pacientes con EII, lo que respalda a CCR9 como una diana altamente relevante para la modulaci\u00f3n selectiva de c\u00e9lulas inmunitarias.<\/p>\n<p data-start=\"1538\" data-end=\"1762\">SunRock ha desarrollado SRB5, un novedoso anticuerpo anti-CCR9 con mayor afinidad por su diana y una actividad citot\u00f3xica celular dependiente de anticuerpos (ADCC) mejorada para la eliminaci\u00f3n de c\u00e9lulas T CCR9+ patog\u00e9nicas.<\/p>\n<h3 data-section-id=\"1x33vog\" data-start=\"1764\" data-end=\"1776\">Oncolog\u00eda<\/h3>\n<p data-start=\"1778\" data-end=\"1988\">El receptor de quimiocinas 9 (CCR9) se encuentra sobreexpresado en tumores s\u00f3lidos y hematol\u00f3gicos. CCR9 promueve la met\u00e1stasis y el desarrollo de resistencia a los tratamientos convencionales en estos tumores.<\/p>\n<p data-start=\"1990\" data-end=\"2211\">SunRock se ha asociado con la plataforma tecnol\u00f3gica de inhibidores de fusi\u00f3n de Escugen Biotechnology para el desarrollo de un conjugado anticuerpo-f\u00e1rmaco (ADC) anti-CCR9 (SRB123) para el tratamiento de tumores s\u00f3lidos.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><a class=\"btn\" href=\"\/es\/ccr9\/\">Ver m\u00e1s<\/a><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row el_id=\u00bbher3&#8243;][vc_column css_animation=\u00bbfadeInLeft\u00bb width=\u00bb1\/2&#8243;][vc_single_image image=\u00bb328&#8243; img_size=\u00bbfull\u00bb alignment=\u00bbcenter\u00bb el_class=\u00bbvisible-xs visible-sm program-img\u00bb][vc_column_text]<\/p>\n<h2>Programa HER3<\/h2>\n<p data-start=\"2256\" data-end=\"2675\">HER3 es una diana terap\u00e9utica validada asociada a la progresi\u00f3n tumoral, la reducci\u00f3n de la supervivencia de los pacientes y el desarrollo de resistencia a las terapias dirigidas contra HER2 y EGFR. Como parte de la familia de receptores del factor de crecimiento epid\u00e9rmico, HER3 desempe\u00f1a un papel clave en la regulaci\u00f3n de distintos tipos tumorales y en la aparici\u00f3n de resistencia a los tratamientos convencionales.<\/p>\n<p data-start=\"2677\" data-end=\"2921\">SunRock ha desarrollado una mol\u00e9cula anti-HER3 con mayor afinidad y un novedoso mecanismo de acci\u00f3n dise\u00f1ado para superar los mecanismos de resistencia y mejorar la eficacia antitumoral en comparaci\u00f3n con otros enfoques dirigidos frente a HER3.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><a class=\"btn\" href=\"\/es\/her3\/\">Ver m\u00e1s<\/a><\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column css_animation=\u00bbfadeInRight\u00bb width=\u00bb1\/2&#8243; el_class=\u00bbprogram-img\u00bb][vc_single_image image=\u00bb328&#8243; img_size=\u00bbfull\u00bb alignment=\u00bbcenter\u00bb el_class=\u00bbhidden-xs hidden-sm\u00bb][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column css_animation=\u00bbfadeInUp\u00bb el_class=\u00bbbox-shadow\u00bb][vc_row_inner][vc_column_inner width=\u00bb1\/2&#8243;][vc_empty_space height=\u00bb80px\u00bb][vc_single_image image=\u00bb20&#8243; img_size=\u00bb\u00bb alignment=\u00bbcenter\u00bb][\/vc_column_inner][vc_column_inner width=\u00bb1\/2&#8243;][vc_empty_space height=\u00bb80px\u00bb el_class=\u00bbhidden-xs hidden-sm\u00bb][vc_column_text]SunRock Biopharma est\u00e1 desarrollando una cartera de anticuerpos first-in-class, ADCs&#8230;<\/p>\n","protected":false},"author":1,"featured_media":557,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_mi_skip_tracking":false,"footnotes":""},"class_list":["post-555","page","type-page","status-publish","has-post-thumbnail","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - 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